James coins the phrase "medical materialism" for the tendency to discredit religious experiences by showing they have organic correlates or pathological antecedents. George Fox was psychotic; Teresa of Ávila was hysterical; Paul's conversion was an epileptic seizure. Therefore — the argument runs — their religious insights have no validity. James accepts the empirical claims and denies the inference.
The same principle that medical materialism uses to discredit religion applies equally to science, art, and every other human achievement. Newton's genius can be attributed to his psychological constitution; Darwin's insight emerged partly from his chronic illness. Nobody concludes that gravity is therefore unreal or natural selection mistaken. We judge the fruits — the practical and intellectual consequences — not the roots. Religious experience must be treated by the same standard.
James proposes three positive criteria for evaluating religious states: immediate luminousness (is the experience vivid and compelling from inside?), philosophical reasonableness (does it cohere with what else we know?), and moral helpfulness (does it make better people?). These are not proofs of supernatural origin — they are empirical tests of value. They are the tests by which any state of mind, religious or secular, must ultimately stand or fall.
The argument against medical materialism occupies Lecture I of The Varieties of Religious Experience (1902). It remains the foundational methodological statement of the empirical study of religion.
